对应专业:Pharmaceutical Sciences or related field or foreign equivalent degree
所需培训:N
培训时长:
所需培训领域:
前置经验:N
经验时长（月）:
替代领域学历:N
替代专业:
可替代教育及经验组合:N
所需教育层级:
其他可替代教育层级:
认可经验年限:
境外教育背景:Y
可替代职业:Y
可替代职业时长（月）:24
可替代职业名称:Associate Scientist, Intern Clinical Pharmacology, Research Assistant, Teaching Assistant or relat
是否为正常职业要求:Y
是否需要外语:N
特殊技能:PhD degree in Pharmaceutical Sciences or related field or foreign equivalent degree. REQUIRED SKILLS Execute mediumthroughput screening assays to understand the potential of lead drug candidates to induce cytochrome P450 enzymes. Conduct the in vitro enzyme induction assays to predict the clinical drug interactions. Develop the physiologicallybased pharmacokinetic PBPK models using SimCYP to capture the plasma profiles of pregabalin and dacocitinib. Extrapolate the PK profiles from Caucasian to Chinese population to validate the SimCYPs ability to predict the ethnicity based difference on drug disposition. Use SimCYP as platform to learn PBPK modeling to predict the drug disposition in humans. Use knowledge of human physiology including structure of the central nervous system CNS to design delivery of drugs to the CNS.